Description
Medical Microbiology and Infection Lecture Notes
is ideal for medical students, junior doctors, pharmacy students,
junior pharmacists, nurses, and those training in the allied health
professions. It presents a thorough introduction and overview of this
core subject area, and has been fully revised and updated to include:
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Chapters written by leading experts reflecting current research and teaching practice
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New chapters covering Diagnosis of Infections and Epidemiology and Prevention & Management of Infections
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Integrated full-colour illustrations and clinical images
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A self-assessment section to test understanding
Table of Contents
Preface v
Contributors vii
Basic microbiology
1 Basic bacteriology 3
Peter Lambert
2 Classification of bacteria 12
Peter Lambert
3 Staphylococci 16
Tom Elliott and Peter Lambert
4 Streptococci and enterococcci 20
Anna Casey
5 Clostridia 26
Tony Worthington
6 Other Gram-positive bacteria 30
Anna Casey
7 Gram-negative cocci 36
Jonathan Sandoe
8 Enterobacteriaceae 40
Peter Lambert
9 Haemophilus and other fastidious Gram-negative bacteria 45
Jonathan Sandoe
10 Pseudomonas Legionella and other environmental Gram-negative bacilli 51
Peter Lambert
11 Campylobacter Helicobacter and Vibrio 54
Martin Skirrow Cliodna McNulty and Tom Elliott
12 Treponema Borrelia and Leptospira 58
Susan O’Connell
13 Gram-negative anaerobic bacteria 62
Peter Lambert
14 Chlamydiaceae Rickettsia Coxiella Mycoplasmataceae and Anaplasmataceae 64
Jonathan Sandoe
15 Basic virology 6
Peter Mackie
16 Major virus groups 75
Peter Mackie
17 Basic mycology and classification of fungi 93
Elizabeth Johnson
18 Parasitology: protozoa 101
Peter Chiodini
19 Parasitology: helminths 112
Peter Chiodini
Antimicrobial agents
20 Antibacterial agents 127
Peter Lambert
21 Antifungal agents 144
Elizabeth Johnson
22 Antiviral agents 147
Eleni Nastouli
Infection
23 Diagnostic laboratory methods 157
Tony Worthington
24 Epidemiology and prevention of infection 167
Barry Cookson
25 Upper respiratory tract infections 177
Jonathan Sandoe
26 Lower respiratory tract infections 183
Shruti Khurana
27 Tuberculosis and mycobacteria 189
Sumeet Singhania
28 Gastrointestinal infections 193
Tariq Iqbal
29 Liver and biliary tract infections 202
David Mutimer
30 Urinary tract infections 207
Chris Catchpole
31 Genital infections 210
Kaveh Manavi
32 Infections of the central nervous system 220
Erwin Brown
33 Bacteraemia and bloodstream infections 229
Tom Elliott
34 Device-related infections 233
Tom Elliott
35 Cardiovascular infections 238
Richard Watkin
36 Bone and joint infections 241
Jonathan Sandoe
37 Skin and soft-tissue infections 246
Supriya Narasimhan and Rabih Darouiche
38 Infections in the compromised host 257
Tom Elliott
39 Infections caused by antimicrobial-resistant bacteria 260
David Livermore
40 Perinatal and congenital infections 264
James Gray
41 Human immunodeficiency virus 271
Kaveh Manavi
42 Miscellaneous viral infections 277
John Cheesbrough
Self-assessment
Self-assessment questions 285
Answers to self-assessment questions 300
General subject index 309
Organism index 317
Contributors vii
Basic microbiology
1 Basic bacteriology 3
Peter Lambert
2 Classification of bacteria 12
Peter Lambert
3 Staphylococci 16
Tom Elliott and Peter Lambert
4 Streptococci and enterococcci 20
Anna Casey
5 Clostridia 26
Tony Worthington
6 Other Gram-positive bacteria 30
Anna Casey
7 Gram-negative cocci 36
Jonathan Sandoe
8 Enterobacteriaceae 40
Peter Lambert
9 Haemophilus and other fastidious Gram-negative bacteria 45
Jonathan Sandoe
10 Pseudomonas Legionella and other environmental Gram-negative bacilli 51
Peter Lambert
11 Campylobacter Helicobacter and Vibrio 54
Martin Skirrow Cliodna McNulty and Tom Elliott
12 Treponema Borrelia and Leptospira 58
Susan O’Connell
13 Gram-negative anaerobic bacteria 62
Peter Lambert
14 Chlamydiaceae Rickettsia Coxiella Mycoplasmataceae and Anaplasmataceae 64
Jonathan Sandoe
15 Basic virology 6
Peter Mackie
16 Major virus groups 75
Peter Mackie
17 Basic mycology and classification of fungi 93
Elizabeth Johnson
18 Parasitology: protozoa 101
Peter Chiodini
19 Parasitology: helminths 112
Peter Chiodini
Antimicrobial agents
20 Antibacterial agents 127
Peter Lambert
21 Antifungal agents 144
Elizabeth Johnson
22 Antiviral agents 147
Eleni Nastouli
Infection
23 Diagnostic laboratory methods 157
Tony Worthington
24 Epidemiology and prevention of infection 167
Barry Cookson
25 Upper respiratory tract infections 177
Jonathan Sandoe
26 Lower respiratory tract infections 183
Shruti Khurana
27 Tuberculosis and mycobacteria 189
Sumeet Singhania
28 Gastrointestinal infections 193
Tariq Iqbal
29 Liver and biliary tract infections 202
David Mutimer
30 Urinary tract infections 207
Chris Catchpole
31 Genital infections 210
Kaveh Manavi
32 Infections of the central nervous system 220
Erwin Brown
33 Bacteraemia and bloodstream infections 229
Tom Elliott
34 Device-related infections 233
Tom Elliott
35 Cardiovascular infections 238
Richard Watkin
36 Bone and joint infections 241
Jonathan Sandoe
37 Skin and soft-tissue infections 246
Supriya Narasimhan and Rabih Darouiche
38 Infections in the compromised host 257
Tom Elliott
39 Infections caused by antimicrobial-resistant bacteria 260
David Livermore
40 Perinatal and congenital infections 264
James Gray
41 Human immunodeficiency virus 271
Kaveh Manavi
42 Miscellaneous viral infections 277
John Cheesbrough
Self-assessment
Self-assessment questions 285
Answers to self-assessment questions 300
General subject index 309
Organism index 317
Author Information
Tom Elliott
is Consultant Medical Microbiologist at The Queen Elizabeth Hospital,
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Anna Casey is Clinical Research Scientist in the Department of
Clinical Microbiology at The Queen Elizabeth Hospital, University
Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Peter Lambert is Professor of Microbiology in the School of Life and Health Sciences at Aston University, Birmingham, UK
Jonathan Sandoe is Consultant Microbiologist and Honorary Senior Lecturer in the Department of Microbiology at Leeds Teaching Hospitals NHS Trust and University of Leeds, Leeds, UK
Peter Lambert is Professor of Microbiology in the School of Life and Health Sciences at Aston University, Birmingham, UK
Jonathan Sandoe is Consultant Microbiologist and Honorary Senior Lecturer in the Department of Microbiology at Leeds Teaching Hospitals NHS Trust and University of Leeds, Leeds, UK
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